RIFAXIMIN-MEDIATED GUT MICROBIOTA REGULATION MODULATES THE FUNCTION OF MICROGLIA AND PROTECTS AGAINST CUMS-INDUCED DEPRESSION-LIKE BEHAVIORS IN ADOLESCENT RAT

Abstract Background Chronic unpredictable mild stress (CUMS) can not only lead to depression-like behavior but also change the composition of the gut microbiome.Regulating the gut microbiome can have an antidepressant effect, but the mechanism by which it improves depressive symptoms is not clear.Short-chain fatty acids (SCFAs) are small molecular

Global climate change has become one of the core issues of world governance.Many countries have put forward the goal of carbon neutrality one after another, leading to the intensification of international low-carbon economy competition.To assess the current low-carbon competitiveness among countries, this article constructs an evaluation index syst

Sulforaphane (SFN) is a naturally occurring isothiocyanate that is abundant in many cruciferous vegetables, such as broccoli and cauliflower, and it has been observed to exert numerous biological activities.In the present study, we investigate the effect of SFN on eNOS, a key regulatory enzyme read more of vascular homeostasis and underlying intrac

The replica beach walk candle on-board safety computer of Chinese Train Control System generates a large number of Log files during operation every day, which together with the quality analysis record sheet, record the running status of all equipment and provide data support for the fault discovery and processing of the equipment of train control s